Details for gene set BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos
Phenotype	phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos
Upregulated in class	wtNotch
GeneSet	BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION
Enrichment Score (ES)	-0.9005528
Normalized Enrichment Score (NES)	-1.4954451
Nominal p-value	0.026143791
FDR q-value	0.42806962
FWER p-Value	1.0

Fig 1: Enrichment plot: BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PTPRC	130402 5290148	2453	0.091	-0.1221	No
2	CD247	3800725 5720136	2736	0.074	-0.1294	No
3	FYN	2100468 4760520 4850687	3063	0.058	-0.1407	No
4	LCK	3360142	15797	-0.069	-0.8177	No
5	CD4	1090010	16262	-0.094	-0.8326	No
6	CD3E	3800056	16914	-0.148	-0.8518	No
7	ZAP70	1410494 2260504	17495	-0.237	-0.8577	Yes
8	CD3G	2680288	18293	-0.577	-0.8390	Yes
9	CD3D	2810739	18351	-0.648	-0.7728	Yes
10	TRB@	3940292	18616	-7.377	-0.0000	Yes

Fig 2: BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION: Random ES distribution
Gene set null distribution of ES for BIOCARTA_LCK AND FYN TYROSINE KINASES IN INITIATION OF TCR ACTIVATION